Amin Reza Zolghadr
Assistant Professor
Office: D-211
Phone: +98 713 613 7175
Email: arzolghadr@shirazu.ac.ir
Education and Appointments
B.Sc. in Pure Chemistry: Sistan & Baluchestan University, Iran (Feb. 2000-Sep.2004)
M.Sc. in Physical Chemistry: Shiraz Univ., Iran, (Sep.2004-Sep. 2006)
Ph.D. in Physical Chemistry: Shiraz Univ., Iran, (Sep.2006- Feb 2010)
Assistant Prof., Shiraz Univ. of Medical Science, Iran, (Feb. 2012- Jun 2013)
Assistant Prof., Shiraz Univ., Iran, (since Jun 2013)
Research Interests
Statistical Mechanics, Surface Chemistry , Car-Parrinello Molecular Dynamics Simulation,
Molecular Dynamics Simulation of Ionic Liquids, Molecular Dynamics Simulation of Biological systems
Publication Cover Art
Our molecular dynamics simulations show that aminopropyl dibromocarbazole derivative (P7C3) treat Alzheimer Disease by prevention of Aβ fibrils deposition into the cell membrane. The P7C3 small molecules are self-assembled at membrane/ionic aqueous solution interface and prevent membrane disruption by binding to the Aβ peptides. The introduction of P7C3 class of neuroprotective small molecules opens up a new avenue to develop novel Alzheimer’s drug.
A. R. Zolghadr* and M. Heydari Dokoohaki, How Does the P7C3-Series of Neuroprotective Small Molecules Prevent Membrane Disruption? J. Chem. Inf. Model., 2017, 57 (8), pp 2009–2019
Selected Publications
Spontaneous assembly of HSP90 inhibitors at water/octanol interface: A molecular dynamics simulation study
A.R. Zolghadr*, S. Boroomand
Chemical Physics Letters 669 (2017) 130-136
Self-assembly of neuroprotective carbazolium based small molecules at octane/water interface: A simulation investigation
A.R. Zolghadr*, M. Heydari Dokoohaki
Chemical Physics 480 (2016) 1–11
The effect of various quantum mechanically derived partial atomic charges on the bulk properties of chloride-based ionic liquids
A. R. Zolghadr*, M. H. Ghateea, F. Moosavi
Chemical Physics 475 (2016) 23–31
Z. Faghih, M. Fereidoonnezhad, S. M. H. Tabaei, Z. Rezaei, A. R. Zolghadr*
Chemical Physics, 459 (2015) 31–39
doi:10.1016/j.chemphys.2015.07.026
Adsorption and Orientation of Ionic Liquids and Ionic Surfactants at Heptane/Water Interface
J. Phys. Chem. C, 2014, 118:19889-19903
A. R. Zolghadr,* M. H. Ghatee , A. Zolghadr
Local Depolarization in Hydrophobic and Hydrophilic Ionic Liquids-Water Mixtures: Car–Parrinello and Classical Molecular Dynamics Simulation
M. H. Ghatee* and A. R. Zolghadr
J. Phys. Chem. C, 2013, 117:2066-2077
Studies of structural, dynamical and interfacial properties of 1-alkyl-3-methylimidazolium iodide ionic liquids by molecular dynamics simulation
M. H. Ghatee* and A. R. Zolghadr. F. Moosavi, Y. Ansari
J. Chem. Phys., 2012 136:124706-14
Surface tension measurements of imidazolium based ionic liquids at liquid/vapor equilibrium
M. H. Ghatee* and A. R. Zolghadr
Fluid Phase Equilibria, 2008 263 :168-175
Recent Comments